Population
Dogs anesthetized with sodium pentobarbital (group I) and with methoxyflurane (group II)
Comparison
Methoxyflurane anesthesia and beta-adrenergic… vs Sodium pentobarbital anesthesia
Design
Preclinical
Authors
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Animal data on anesthesia and beta-blockade effects require clinical confirmation before influencing practice; leaves open applicability to human hemodynamics.
The study demonstrates that systemic pressure-flow and volume-flow relationships in dogs are nonlinear and are significantly altered by the type of anesthesia and beta-adrenergic blockade.
JF Green (1975) studied this question.
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