Modeling of Coronary Artery Balloon-Angioplasty Using Equivalent Electrical Circuit

Arterial thrombosis and atherosclerosis result in chronic total or partial occlusion of the coronary artery. Coronary artery disease (CAD) destroys some parts of the heart muscle tissue and is the leading cause of human deaths in the industrialized world. In this study, cardiovascular system is simulated by 42 compartments and then a coronary set (including artery, venous, myocardium and capillaries) is added to the model. Each vessel is modeled by three parameters, such as resistor, capacitor and inductor. These three parameters are variable with respect to the radius of the vessel. In this paper, first of all, aortic and coronary flow under healthy condition is studied. The obtained results are in complete agreement with experimental outcomes. Then cardiovascular system behavior in coronary artery stenosis condition is investigated. Finally, the effect of intra-coronary balloon pump on heart attack risk and also on stabilization of patient's emergency condition by mathematical simulation is analyzed. The results of modeling show that the balloon pumping of coronary artery is an advantageous way in rendering primary cure to patients. The proposed model, in addition, has implications for investigation of effects of different diseases on the cardiovascular system. It also has the potential to model different treatment methods on heart's performance and, as a result, recommend new methods in order to cure variant cardiovascular diseases.