February 5, 2017Magnetic Resonance in MedicineOpen Access

In vivo quantification of aortic stiffness using MR elastography in hypertensive porcine model

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Population

8 pigs with systemic arterial hypertension induced by renal wrapping surgery

Comparison

MR elastography using a retrospectively… vs Invasive central aortic pressure measurements

Design

Preclinical

Follow-up

2 months

Authors

HDHui‐Ming DongSan Francisco VA Medical Center RMRia MazumderWidener University VIVenkata Sita Priyanka IllapaniCincinnati Children's Hospital Medical Center

Discussion

Member takes

Implication

Aortic MRE shows promise in hypertensive porcine models; leaves open validation and outcome correlation in human cohorts.

Structured PICO

Population

8 pigs with systemic arterial hypertension induced by renal wrapping surgery

Intervention

MR elastography (MRE) using a retrospectively pulse-gated gradient-echo sequence on a 1.5 tesla scanner

Comparator

Invasive central aortic pressure measurements (mean arterial pressure)

Outcome

Effective aortic stiffness and its correlation with mean arterial pressuresurrogate

MR elastography can non-invasively quantify aortic stiffness, which correlates with invasive mean arterial pressure in a hypertensive porcine model.

Cite This Study

Dong et al. (2017) studied this question.

synapsesocial.com/papers/6a710049e36a167817e2d49d https://doi.org/10.1002/mrm.26601

Topics

Hypertension management

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In vivo quantification of aortic stiffness using MR elastography in hypertensive porcine model

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

In vivo quantification of aortic stiffness using MR elastography in hypertensive porcine model

Discussion

Member takes

Implication

Structured PICO

Cite This Study

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Topics

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