Why the study?
Does the Björk-Shiley valve reduce mechanical haemolysis compared to Starr-Edwards and Kay-Shiley valves in an in vitro model?
Does the Björk-Shiley valve reduce mechanical haemolysis compared to Starr-Edwards and Kay-Shiley valves in an in vitro model?
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In vitro testing demonstrates that Björk-Shiley valves produce lower rates of haemolysis compared to Starr-Edwards and Kay-Shiley valves due to improved haemodynamic characteristics.
Mechanical cell damage was studied in vitro with three types of prostheses: Starr-Edwards, Kay-Shiley and Björk-Shiley valves. Mechanical cell damage was found to be closely related to the flow characteristics in the prosthesis. Considering valves of similar orifice diameter, Björk-Shiley valves produced the lowest rate of haemolysis. This is due to the improved haemodynamic characteristics of the valve which resulted from the laminar type of flow. With Starr-Edwards valves, smaller sizes produced unacceptably high rates of haemolysis. Increasing the mean forward flow across the valve resulted in a disproportionate rise in the energy loss and the rate of haemolysis when compared with Björk-Shiley valves of similar annulus diameters.
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Sallam et al. (1976) studied this question.
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