Why the study?
Does immune electronmicroscopy provide accurate typing of enteroviruses compared to neutralisation in cell culture?
Population
50 picornavirus strains (including enteroviruses and rhinoviruses)
Comparison
Immune electronmicroscopy (IEM) for viral typing vs Neutralisation in cell culture
Design
Preclinical
Authors
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IEM matches neutralisation for most enterovirus strains in animal models; leaves open clinical adoption pending human validation.
Does immune electronmicroscopy provide accurate typing of enteroviruses compared to neutralisation in cell culture?
Immune electronmicroscopy is a convenient and accurate method for typing enteroviruses, offering savings in time and reagents compared to cell culture neutralisation.
Lee et al. (1996) studied this question.
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