What question did this study set out to answer?

To evaluate the long-term stability and efficacy of chronic low-output epicardial pacing using steroid-eluting electrodes over a six-year period in a pediatric population.

December 1, 1997Pacing and Clinical Electrophysiology

Steroid‐Eluting Epicardial Pacing Electrodes: Six Year Experience of Pacing Thresholds in a Growing Pediatric Population

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Why the study?

Does epicardial pacing with steroid-eluting electrodes maintain stable low pacing thresholds in pediatric patients?

Population

22 pediatric patients requiring pacemaker implantation, including those with and without prior cardiac…

Design

Cohort

Follow-up

up to 6 years

Authors

NCNancy CutlerBeaumont Hospital, Royal Oak PKPeter P. KarpawichChildren's Hospital of Michigan DCDianne L. CavittWayne State University

Discussion

Member takes

Implication

Supports long-term use of steroid-eluting epicardial leads in children; extends observational data but leaves open randomized confirmation.

Key Points

To evaluate the long-term stability and efficacy of chronic low-output epicardial pacing using steroid-eluting electrodes over a six-year period in a pediatric population.
Prospective study of 22 pediatric patients (ages 2 days to 18.5 years, median 3.5 years) implanted with 26 steroid-eluting epicardial leads and followed for up to 6 years.
Assessed chronic pulse width thresholds at 2.5 V according to lead implant chamber (atrium vs. ventricle) and history of prior cardiac surgery.
The acute implant mean pulse width threshold at 2.5 V was 0.10 ± 0.05 ms across all electrodes, remaining stable for up to 6 years without significant variation.
Mean ventricular pulse width thresholds were significantly higher than atrial thresholds at implant and throughout the 6-year period (0.12 ± 0.05 ms vs. 0.06 ± 0.03 ms, P < 0.001).
Pacing thresholds in patients with prior cardiac surgery were comparable to those without prior cardiac surgery (P = NS).

Structured PICO

Does epicardial pacing with steroid-eluting electrodes maintain stable low pacing thresholds in pediatric patients?

Population

22 pediatric patients (ages 2 days-18.5 years, median 3.5 years) requiring pacemaker implantation, including those with and without prior cardiac surgery.

Intervention

Implantation of steroid-eluting epicardial pacing electrodes (total 26 leads).

Outcome

Stability of chronic pulse width thresholds at 2.5 V over up to 6 years.surrogate

Steroid-eluting epicardial pacing electrodes maintain stable low pacing thresholds for up to 6 years in pediatric patients, regardless of pacing site or prior cardiac surgery.

Cite This Study

Cutler et al. (1997) studied this question.

synapsesocial.com/papers/6a71a6eb3ce530166bc3268e https://doi.org/10.1111/j.1540-8159.1997.tb05464.x

Topics

Congenital heart disease adults

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Implication

Supports long-term use of steroid-eluting epicardial leads in children; extends observational data but leaves open randomized confirmation.

Steroid‐Eluting Epicardial Pacing Electrodes: Six Year Experience of Pacing Thresholds in a Growing Pediatric Population

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Steroid‐Eluting Epicardial Pacing Electrodes: Six Year Experience of Pacing Thresholds in a Growing Pediatric Population

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Topics

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