Why the study?
Does nitrous oxide included in anesthesia cause hepatic injury in young or old patients undergoing total hip replacement?
Population
100 young and old patients having total hip replacements
Comparison
Nitrous oxide included during regional… vs Regional anesthesia supplemented with isoflurane…
Design
RCT, randomly assigned
Follow-up
3 days
Authors
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Supports N2O use in hip replacement anesthesia without added hepatic monitoring; confirms safety across ages in this RCT.
Does nitrous oxide included in anesthesia cause hepatic injury in young or old patients undergoing total hip replacement?
The inclusion of nitrous oxide during regional anesthesia for total hip replacement does not cause hepatic injury in young or old patients.
Lampe et al. (1990) studied this question.
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