Population
62 consecutive patients with acute myocardial infarction admitted to the Myocardial Infarction Research Unit.
Design
Cohort
Follow-up
first 4 days after admission
Authors
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Supports adaptive O2 extraction in AMI; hypothesis-generating for hemoglobin affinity modulation, should not yet change practice.
In patients with acute myocardial infarction, reduced arterial oxygen flow rate is compensated by increased proportional oxygen extraction, which is partially facilitated by a reduction in hemoglobin-oxygen affinity.
Lichtman et al. (1974) studied this question.
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