Why the study?
Does breathing different concentrations of oxygen affect haemodynamic and biochemical parameters in patients with acute myocardial infarction?
Does breathing different concentrations of oxygen affect haemodynamic and biochemical parameters in patients with acute myocardial infarction?
Oxygen administration in acute myocardial infarction increases peripheral resistance and arterial pressure without changing cardiac output.
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Alerts to hemodynamic effects of supplemental oxygen in AMI; leaves open whether time or concentration drives metabolic changes.
Haemodynamic and biochemical studies while breathing four different concentrations of oxygen showed increases in peripheral resistance and arterial pressure without an appreciable change in cardiac output. The patients with low cardiac outputs had lower arterial pO2 values. Lactate and pyruvate levels declined with time rather than the concentration of oxygen.
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Foster et al. (1969) studied this question.
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