What does this research mean for the field?

Breathing 100% oxygen in healthy men causes statistically significant decreases in cardiac index and heart rate, alongside persistent increases in peripheral vascular resistance and arterial blood pressure. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

January 1, 1962Journal of Applied Physiology

Hemodynamic responses to oxygen breathing in man

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Why the study?

Does breathing 100% oxygen alter hemodynamic parameters in healthy male volunteers?

Population

8 healthy male volunteers

Design

Other

Follow-up

40 min after oxygen was discontinued

Authors

GEG. W. N. EggersOLVG HPH.W. PaleyUniversity of Maryland, Baltimore JLJames J. LeonardGeorgetown University

Discussion

Member takes

Implication

Warrants caution with high-flow oxygen in vulnerable patients; leaves open effects and mechanisms in cardiovascular disease.

Structured PICO

Does breathing 100% oxygen alter hemodynamic parameters in healthy male volunteers?

Population

8 healthy male volunteers

Intervention

Breathing 100% oxygen for an average of 30 min

Outcome

Hemodynamic responses including cardiac output, cardiac index, heart rate, central blood volume, peripheral vascular resistance, and arterial pressuressurrogate

Breathing 100% oxygen causes significant acute hemodynamic changes, including decreased cardiac index and increased vascular resistance and blood pressure in healthy men.

Cite This Study

Eggers et al. (1962) studied this question.

synapsesocial.com/papers/6a18da7da09e0bfd307c11f8 https://doi.org/10.1152/jappl.1962.17.1.75

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Hemodynamic responses to oxygen breathing in man

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Hemodynamic responses to oxygen breathing in man

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider