Why the study?
Does oral enalapril premedication attenuate the blood pressure response to tracheal intubation and stabilize postoperative blood pressure in neurovascular patients undergoing craniotomy?
Population
22 patients subjected to craniotomy and ligation of an intracranial aneurysm or extirpation of an…
Comparison
Oral premedication with enalapril, 0.1 mg/kg vs Placebo
Design
Other
Follow-up
Postoperative period in the intensive care unit
Authors
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Supports enalapril premedication for hemodynamic stability in craniotomy; extends ACE inhibitor evidence in neuroanesthesia.
Does oral enalapril premedication attenuate the blood pressure response to tracheal intubation and stabilize postoperative blood pressure in neurovascular patients undergoing craniotomy?
Enalapril premedication is favorable for hypotensive anesthesia in neurovascular patients by attenuating hypertensive responses to intubation and stabilizing postoperative blood pressure.
Tohmo et al. (1993) studied this question.
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