Why the study?
Does enalapril pretreatment reduce the pressor response to tracheal intubation and surgical stimulation in surgical patients?
Population
22 patients undergoing surgery requiring tracheal intubation
Comparison
Enalapril 5 mg given 4 hours before operation vs Control
Design
Other
Authors
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May support hemodynamic stability in select surgical patients; leaves open confirmation via randomized trials before practice change.
Does enalapril pretreatment reduce the pressor response to tracheal intubation and surgical stimulation in surgical patients?
Preoperative administration of enalapril reduces the pressor response to intubation and surgical stimulation, potentially improving peri-operative cardiovascular stability.
Yates et al. (1988) studied this question.
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