Population
Porcine heart model
Comparison
Ischaemic preconditioning induced by two… vs Control regions (normal myocardium)
Design
Preclinical
Follow-up
30 min after the last occlusion
Authors
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Ischaemic preconditioning leaves antioxidant defence and G-protein signalling unchanged in porcine myocardium; leaves open alternative cardioprotective mechanisms for further study.
Ischaemic preconditioning in porcine myocardium does not alter antioxidant defence or G protein mediated receptor signalling, suggesting these mechanisms do not contribute to its cardioprotective effects.
Fu et al. (1993) studied this question.
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