Why the study?
LGE is often a late finding in DMD myocardial remodeling, and native T1 measurements have predominantly been reported at 1.5T rather than 3T.
Does 3T CMR T1-mapping and ECV estimation detect early myocardial remodeling in pediatric patients with Duchenne muscular dystrophy compared to healthy controls?
Does 3T CMR T1-mapping and ECV estimation detect early myocardial remodeling in pediatric patients with Duchenne muscular dystrophy compared to healthy controls?
3T CMR T1-mapping and ECV can detect subclinical myocardial remodeling in boys with Duchenne muscular dystrophy, outperforming conventional LVEF.
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May detect early myocardial remodeling in DMD before LGE; hypothesis-generating pending prospective validation.
Maforo et al. (2020) studied this question.
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