Population
Frog heart preparations (sinus venosus and right atrium)
Comparison
Artificial stretch vs Spontaneously beating hearts
Design
Preclinical
Authors
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Cardiac fibroblasts may mediate stretch sensing in amphibian atrium; leaves open relevance to mammalian hearts or arrhythmias.
Identified mechanosensitive cells in the frog heart atrium as cardiac fibroblasts, with membrane resistance inversely proportional to applied stretch.
Köhl et al. (1992) studied this question.
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