March 1, 1999Experimental Physiology

Mechanically Induced Potentials in Fibroblasts from Human Right Atrium

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Population

Fibroblasts from human right atrium

Design

Preclinical

Authors

AKAndre KamkinPirogov Russian National Research Medical University IKIrina KiselevaUral Federal University KWKay‐Dietrich WagnerCentre National de la Recherche Scientifique

Discussion

Member takes

Implication

Should not alter clinical practice; leaves open fibroblast contributions to human mechano-electrical feedback.

Structured PICO

Population

Fibroblasts from human right atrium

Intervention

Mechanical stretch associated with rhythmic contractions of the myocardium and artificial intracellular polarization

Outcome

Mechanically induced potentials (MIPs) and changes in membrane potentialsurrogate

Human right atrial fibroblasts are mechanosensitive and generate mechanically induced potentials during myocardial contraction, suggesting a potential role in cardiac mechano-electrical feedback.

Cite This Study

Kamkin et al. (1999) studied this question.

synapsesocial.com/papers/6a8cdfa5f37eeef560ff1494 https://doi.org/10.1111/j.1469-445x.1999.01794.x

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Mechanically Induced Potentials in Fibroblasts from Human Right Atrium

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Mechanically Induced Potentials in Fibroblasts from Human Right Atrium

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider