Why the study?
Does nitrendipine lower blood pressure and affect kidney function compared to captopril or their combination in untreated essential mild-to-moderate hypertensives?
Population
30 untreated essential mild-to-moderate hypertensives
Comparison
Nitrendipine 10 mg b.i.d. vs Captopril 50 mg b.i.d. and a combination of…
Follow-up
4 weeks
Authors
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Nitrendipine matches captopril for BP control with added natriuresis and stable renal function; leaves open long-term outcomes versus modern regimens.
Does nitrendipine lower blood pressure and affect kidney function compared to captopril or their combination in untreated essential mild-to-moderate hypertensives?
Nitrendipine alone or in combination with captopril provides similar blood pressure lowering efficacy to captopril alone in mild-to-moderate hypertension.
Glorioso et al. (1988) studied this question.
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