Population
Oocytes expressing the human alpha1C subunit
Design
Preclinical
Authors
Loading...
Animal data suggest beta3 dual modulation of calcium channels; leaves open translation to human cardiac electrophysiology or therapy.
The beta subunit modifies the calcium channel complex through both allosteric modulation of alpha1 subunit function and chaperoning it to the plasma membrane.
Yamaguchi et al. (1998) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: