Why the study?
Does isosorbide-5-mononitrate improve exercise time to the onset of angina in male patients with angina pectoris?
Does isosorbide-5-mononitrate improve exercise time to the onset of angina in male patients with angina pectoris?
Single oral doses of 20 and 40 mg isosorbide-5-mononitrate exert antianginal and anti-ischemic effects for at least up to 6 hours in patients with angina pectoris.
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Supports IS-5MN for acute angina relief; confirms antianginal efficacy on exercise tolerance in this male RCT.
Thadani et al. (1987) studied this question.
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