Why the study?
Does untreated mild essential hypertension alter basal platelet function compared to normotensive controls?
Population
79 men, including 35 40-year-old men with untreated mild essential hypertension and 44 age-matched…
Comparison
Untreated mild essential hypertension (exposure) vs Age-matched normotensive men
Design
Case-control
Authors
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May indicate platelet activation in mild hypertension; leaves open causal role in events and need for prospective trials.
Does untreated mild essential hypertension alter basal platelet function compared to normotensive controls?
Untreated mild essential hypertension is associated with increased platelet activity, particularly in arterial blood, as evidenced by increased platelet size and beta-thromboglobulin release.
Lande et al. (1987) studied this question.
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