Why the study?
Does acadesine extend the window of protection afforded by ischaemic preconditioning in conscious rabbits?
Population
Chronically instrumented, unsedated rabbits with a balloon occluder around a major branch of the left…
Comparison
Acadesine combined with 5 min ischaemic… vs Control, ischaemic preconditioning alone, and…
Design
Preclinical, Animals were randomised to one of seven groups
Authors
Loading...
Acadesine may prolong preconditioning protection in rabbits; leaves open translation to human cardioprotection.
Does acadesine extend the window of protection afforded by ischaemic preconditioning in conscious rabbits?
Acadesine extends the duration of protection from ischaemic preconditioning to at least 4 hours in conscious rabbits.
Burckhartt et al. (1995) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: