Population
Erythrocytes and thrombocytes (blood cells) subjected to high shear tube flow
Design
Preclinical
Authors
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High shear may initiate thrombosis in stenoses or devices; hypothesis-generating for human studies before clinical translation.
High shear stress, such as that found in arterial stenoses or artificial organs, directly contributes to thrombosis by damaging red blood cells and activating platelets.
Schmid‐Schönbein et al. (1981) studied this question.
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