Why the study?
Does a low-fat diet improve endothelial function compared with an isocaloric low-carbohydrate diet in obese healthy volunteers?
Population
20 obese and otherwise healthy volunteers with mean systolic blood pressure 107 to 125 mm Hg.
Comparison
American Heart Association modeled low-fat diet… vs Isocaloric low-carbohydrate Atkins' style diet…
Design
RCT, randomly assigned
Follow-up
6 weeks
Authors
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Low-fat diet improves endothelial function over low-carbohydrate despite equivalent weight loss; challenges dietary equivalence on vascular outcomes in obesity.
Does a low-fat diet improve endothelial function compared with an isocaloric low-carbohydrate diet in obese healthy volunteers?
A low-fat diet improved endothelial function compared to an isocaloric low-carbohydrate diet in obese individuals, despite similar weight loss and blood pressure reductions.
Phillips et al. (2008) studied this question.
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