Why the study?
Does catheter ablation reduce ventricular arrhythmias in patients supported by continuous-flow LVAD?
Does catheter ablation reduce ventricular arrhythmias in patients supported by continuous-flow LVAD?
Catheter ablation for ventricular tachycardia in patients with continuous-flow LVADs is feasible and safe, but arrhythmia recurrence is common.
Supports feasibility of VT ablation in LVAD patients; leaves open durable VA reduction, warranting prospective trials.
Ventricular arrhythmias (VAs) are common after implantation of a left ventricular assist device (LVAD) and in a subset of patients may be refractory to medication. Morbidity from VA in this population includes right ventricular failure (RVF). We sought to evaluate the efficacy of catheter ablation for VA in patients with LVAD. A retrospective analysis of patients supported by continuous-flow LVAD referred for catheter ablation of ventricular tachycardia (VT) between 2008 and the present was performed. Seven patients were referred for VT ablation an average of 236 ± 292 days after LVAD implantation. Three patients (42.9%) developed RVF in the setting of intractable arrhythmias. A transfemoral approach was used for six patients (85.7%) and an epicardial for one patient (14.3%). The clinical VT was inducible and successfully ablated in six patients (85.7%). The location of these arrhythmias was apical in three cases (42.9%). A total of 13 VTs were ablated in seven patients. Although the majority had reduction in VA frequency, recurrent VAs were observed in six patients (85.7%). One patient (14.3%) experienced a bleeding complication after the procedure. For patients with a high VA burden after LVAD implantation, VT ablation is safe and feasible, but VA frequently recurs.
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Garan et al. (2014) studied this question.
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