Association Between Blood Pressure Variability and Inflammatory Marker in Hypertensive Patients
Population
52 hypertensive patients, mean age 55.9+/-1.5 years, 28 men
Design
Cross-sectional
Authors
Discussion
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Member takes
Implication
Observational BP variability–inflammation link warrants no practice change; leaves open causality and needs longitudinal studies.
Structured PICO
P
Population
52 hypertensive patients, mean age 55.9+/-1.5 years, 28 men
O
Outcome
Association between blood pressure variability (within-subject standard deviation and coefficient of variation) and plasma levels of inflammatory markers (IL-6, TNF-alpha, hs-CRP)surrogate
Blood pressure variability is associated with inflammatory markers such as IL-6 in hypertensive patients, suggesting inflammation may mediate target organ damage.
Cite This Study
Kim et al. (2008) studied this question.