Population
Microvascular endothelial cells from rat epididymal fat pad cultured in vitro, and Krebs-suffused cremaster…
Comparison
Infusion of A23187 or acetylcholine through a… vs Infusion through a line containing microcarrier…
Design
Preclinical
Authors
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Hypothesis-generating in animal microvasculature; leaves open translation to human endothelial function.
Microvascular endothelial cells release endothelium-derived relaxing factor (EDRF) in response to A23187 and acetylcholine, which dilates arterioles in vivo and is blocked by L-NMMA.
Koller et al. (1991) studied this question.
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