Why the study?
Does nifedipine GITS reduce diastolic blood pressure compared to amlodipine in elderly patients with mild-moderate hypertension?
Does nifedipine GITS reduce diastolic blood pressure compared to amlodipine in elderly patients with mild-moderate hypertension?
Nifedipine GITS 30-60 mg is as efficacious and safe as amlodipine 5-10 mg in elderly patients with mild-moderate hypertension, with both agents similarly improving quality of life.
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Supports equivalent DBP control with nifedipine GITS versus amlodipine in elderly hypertension; confirms interchangeable dihydropyridine CCB options for practice and future trials.
Pessina et al. (2001) studied this question.
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