Why the study?
What are the baseline differences between extreme responders and nonresponders to renal denervation?
Population
109 patients who underwent renal denervation from the European Network COordinating research on Renal…
Comparison
Renal denervation (RDN) vs Nonresponders
Design
Cohort
Follow-up
6 months
Key result
Defining extreme blood pressure response to renal denervation by office blood pressure rather than ambulatory blood pressure leads to a major overestimation of the response due to a white-coat effect.
Authors
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Office BP overestimates RDN response via white-coat effect; leaves open whether baseline traits distinguish true ABPM-defined responders.
Observational (n=109)
Yes
What are the baseline differences between extreme responders and nonresponders to renal denervation?
Defining response to renal denervation by office blood pressure overestimates the true effect due to a white-coat effect, highlighting the importance of ambulatory blood pressure monitoring.
Persu et al. (2014) conducted an observational in Hypertension (post-renal denervation) (n=109). Extreme blood pressure response to renal denervation vs. Nonresponders was evaluated on Blood pressure changes 6 months after renal denervation. Defining extreme blood pressure response to renal denervation by office blood pressure rather than ambulatory blood pressure leads to a major overestimation of the response due to a white-coat effect.