Population
Isolated cardiomyocytes from control and streptozotocin-treated diabetic rats
Comparison
Incubation with normal and elevated palmitate… vs Incubation in the absence of ketone bodies
Design
Preclinical
Authors
Loading...
May link ketones to lipotoxicity in diabetic hearts; hypothesis-generating and should not change practice.
Ketone bodies suppress cardiac fatty acid oxidation in diabetic cardiomyocytes, potentially contributing to lipid accumulation in the diabetic heart.
Hasselbaink et al. (2003) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: