Why the study?
Does aspirin compared to acetaminophen alter hemostasis in healthy volunteers and patients with hemophilia?
Population
Normal healthy volunteers and patients with either severe hemophilia A or hemophilia B.
Comparison
Aspirin vs Acetaminophen
Design
Other
Authors
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Aspirin may impair hemostasis in hemophilia; leaves open whether acetaminophen is safer in prospective trials.
Does aspirin compared to acetaminophen alter hemostasis in healthy volunteers and patients with hemophilia?
Acetaminophen is preferred over aspirin in patients where hemostatic impairment is undesirable, such as those with hemophilia, as it does not alter bleeding time or platelet function.
C. Harold Mielke (1981) studied this question.
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