January 1, 1996Thrombosis and Haemostasis

European Concerted Action on Anticoagulation (ECAA) - The Multicentre Calibration of Rabbit and Human ECAA Reference Thromboplastins

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Population

14 representative national laboratories participating in a multicentre calibration exercise

Design

Other

Authors

LPL. PollerCross-Cutting Cardiology TBT W BarrowcliffeNational Institute for Biological Standards and Control ABA.M.H.P. van den BesselaarLeiden University Medical Center

Discussion

Member takes

Implication

Enables precise INR standardization for ECAA field study; leaves open clinical adoption pending validation.

Structured PICO

Population

14 representative national laboratories participating in a multicentre calibration exercise

Intervention

Calibration of two candidate ECAA reference preparations (human plain recombinant reagent and rabbit plain preparation)

Outcome

International Sensitivity Index (ISI) of the two candidate preparationssurrogate

The study successfully calibrated human and rabbit ECAA reference thromboplastins, establishing precise ISI values for use in a large European field study.

Cite This Study

Poller et al. (1996) studied this question.

synapsesocial.com/papers/6a7cb6e1076dbfca02ba628b https://doi.org/10.1055/s-0038-1650695

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Ask AI

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European Concerted Action on Anticoagulation (ECAA) - The Multicentre Calibration of Rabbit and Human ECAA Reference Thromboplastins

Discussion

Member takes

Implication

Structured PICO

Cite This Study

European Concerted Action on Anticoagulation (ECAA) - The Multicentre Calibration of Rabbit and Human ECAA Reference Thromboplastins

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider