Why the study?
Does a computer dosage program improve the achievement of target INR intervals compared to manual dosage in patients on oral anticoagulation?
Population
Patients requiring oral anticoagulation across 5 European centers (clinical study component)
Comparison
Computer dosage program for oral anticoagulation vs Traditional dosage by experienced medical staff
Design
Review, Randomised multicentre investigation (for the clinical study component)
Authors
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May support computer dosing for better INR control; leaves open confirmation in randomized trials before practice change.
Does a computer dosage program improve the achievement of target INR intervals compared to manual dosage in patients on oral anticoagulation?
A computer dosage program for oral anticoagulation significantly improves the achievement of target INR intervals compared to traditional manual dosing.
L. Poller (1998) studied this question.
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