Population
Pre-synchronized cattle (n=102) with follicles reaching 12 mm
Comparison
Intrafollicular injection of Ang II receptor… vs Intrafollicular injection of saline solution
Design
Preclinical
Authors
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AT2 blockade inhibits bovine ovulation; hypothesis-generating for human reproduction and should not change practice.
Angiotensin II plays a pivotal role in the early mechanism of bovine ovulation via the AT2 receptor subtype.
Ferreira et al. (2007) studied this question.
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