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October 9, 2014Journal of Hypertension

Arterial stiffness and SBP variability in children and adolescents

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Why the study?

Are ambulatory blood pressure parameters associated with arterial stiffness in children and adolescents?

Population

138 consecutive young patients (age range 4-20 years) referred to a hypertension center

Design

Cross-sectional

Authors

SSStella StabouliPreventive CardiologySPSofia PapakatsikaApple (Israel)KPKyriaki Papadopoulou‐LegbelouGreek Atomic Energy Commission

Discussion

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Implication

SBP variability may mark arterial stiffness in youth; leaves open whether targeting it alters cf-PWV progression.

Key Points

  • To evaluate the relationship between ambulatory blood pressure parameters and arterial stiffness measured by carotid-femoral pulse wave velocity in children and adolescents.
  • Assessed 138 consecutive young patients aged 4 to 20 years referred to a hypertension center.
  • Conducted office blood pressure, 24-hour ambulatory blood pressure monitoring, and carotid-femoral pulse wave velocity (cf-PWV) measurements.
  • Hypertensive patients exhibited higher cf-PWV values than normotensive patients after adjusting for age and sex, with 10.6% exceeding the 95th percentile.
  • Analysis of covariance identified weighted 24-hour SBP variability (β = 0.28, P < 0.05) and daytime SBP variability (β = 0.15, P < 0.05) as the sole independent determinants of cf-PWV.

Structured PICO

Are ambulatory blood pressure parameters associated with arterial stiffness in children and adolescents?

P
Population
138 consecutive young patients (age range 4-20 years) referred to a hypertension center
I
Intervention
Ambulatory blood pressure parameters (specifically SBP variability)
O
Outcome
Arterial stiffness measured by carotid-femoral pulse wave velocity (cf-PWV)surrogate

Increased systolic blood pressure variability is independently associated with arterial stiffness in children and adolescents.

Cite This Study

Stabouli et al. (2014) studied this question.

synapsesocial.com/papers/6a7cec6a448628eb7e2fa6b8https://doi.org/10.1097/hjh.0000000000000369

Topics

Hypertension management
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Also Consider

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