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September 27, 2023Current Opinion in Nephrology & HypertensionOpen Access

Blood pressure targets in chronic kidney disease: still no consensus

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Why the study?

Despite consensus that treating hypertension slows CKD progression and reduces cardiovascular risk, controversy persists regarding optimal blood pressure targets.

What is the optimal blood pressure target to slow CKD progression and reduce cardiovascular events in patients with chronic kidney disease?

Design

Review

Authors

BLBethany LucasMTMaarten W. Taal

Discussion

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Overview

BP targets in CKD lack consensus; leaves open need for definitive trials to guide practice.

Structured PICO

What is the optimal blood pressure target to slow CKD progression and reduce cardiovascular events in patients with chronic kidney disease?

P
Population
Patients with chronic kidney disease (CKD) and hypertension
I
Intervention
Lower blood pressure targets (e.g., systolic BP <120 mmHg or <130/80 mmHg)
C
Comparator
Standard blood pressure targets
O
Outcome
CKD progression and cardiovascular events (CVE)

Due to conflicting evidence and guideline recommendations regarding optimal BP targets in CKD, an individualized approach guided by standardized BP measurement is recommended.

Cite This Study

Lucas et al. (2023) studied this question.

synapsesocial.com/papers/6a7cf76e1e80ecf5247bf95dhttps://doi.org/10.1097/mnh.0000000000000920
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Pros and cons of lower blood pressure targets in chronic kidney disease2025
  2. 2Blood pressure goal in chronic kidney disease: what is the evidence?2011 · 10 citations
  3. 3What Is Wrong with the Blood Pressure Target Recommendation of KDIGO 2021 for Hypertension in Chronic Kidney Disease?2023 · 5 citations
  4. 4Systematic Review: Blood Pressure Target in Chronic Kidney Disease and Proteinuria as an Effect Modifier2011 · 343 citations
  5. 5Optimal targets for blood pressure control in chronic kidney disease2014 · 6 citations