Key result
A blood pressure goal of less than 130/80 mmHg compared to a less aggressive goal neither saves lives nor protects the kidney or cardiovascular system in patients with chronic kidney disease.
Why the study?
Does an aggressive blood pressure goal of less than 130/80 mmHg improve survival, kidney, or cardiovascular outcomes in patients with chronic kidney disease compared to a less aggressive goal?
Population
Patients with chronic kidney disease (CKD)
Comparison
Aggressive blood pressure goal of less than… vs Less aggressive blood pressure goal
Design
Review
Authors
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No outcome benefit from <130/80 mmHg in CKD; leaves open optimal targets for future trials.
Does an aggressive blood pressure goal of less than 130/80 mmHg improve survival, kidney, or cardiovascular outcomes in patients with chronic kidney disease compared to a less aggressive goal?
Current evidence from randomized trials does not support a blood pressure target of <130/80 mmHg over <140/90 mmHg for improving clinical outcomes in patients with chronic kidney disease.
Rajiv Agarwal (2011) conducted a review in chronic kidney disease (CKD). Blood pressure goal of less than 130/80 mmHg vs. Less aggressive BP goal was evaluated on Survival, kidney protection, or cardiovascular protection. A blood pressure goal of less than 130/80 mmHg compared to a less aggressive goal neither saves lives nor protects the kidney or cardiovascular system in patients with chronic kidney disease.
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