Why the study?
Are angiotensin II type 1 and type 2 receptor gene polymorphisms associated with essential hypertension and left ventricular mass in Japanese subjects?
Population
536 Japanese subjects, comprising 321 with essential hypertension and 215 age- and sex-matched normotensive…
Comparison
Angiotensin II type 1 receptor and type 2… vs Normotensive controls and different genotypes
Design
Case-control
Authors
Loading...
AT1/AT2 variants should not guide hypertension risk assessment; leaves open AT1 polymorphism's association with LV mass in normotensives.
Are angiotensin II type 1 and type 2 receptor gene polymorphisms associated with essential hypertension and left ventricular mass in Japanese subjects?
AT1 and AT2 receptor gene polymorphisms do not appear to increase the genetic risk for essential hypertension in Japanese subjects, though the AT1 polymorphism may contribute to increased left ventricular mass.
S. Takami (1998) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: