Why the study?
Does single oral doses of DPI 201-106 alter systolic time intervals and electrocardiogram parameters in healthy volunteers?
Population
20 healthy volunteers
Design
Other, double-blind
Follow-up
1 to 15 hours
Authors
Loading...
Supports heart failure trials; extends systolic time interval data to DPI 201-106 in volunteers.
Does single oral doses of DPI 201-106 alter systolic time intervals and electrocardiogram parameters in healthy volunteers?
DPI 201-106 demonstrates dose-dependent positive inotropic and negative chronotropic effects in healthy volunteers, suggesting potential utility in heart failure.
Rüegg et al. (1987) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: