Why the study?
Does intravenous DPI 201-106 improve acute haemodynamic parameters in patients with moderate cardiac failure?
Population
10 patients with moderate cardiac failure
Design
Case_series
Follow-up
up to 1 h following infusion
Authors
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Should not change practice in cardiac failure; hypothesis-generating for DPI 201-106 hemodynamic effects.
Does intravenous DPI 201-106 improve acute haemodynamic parameters in patients with moderate cardiac failure?
A single intravenous dose of the novel compound DPI 201-106 produces immediate, significant improvements in cardiac index, pulmonary pressures, and ejection fraction in patients with moderate cardiac failure.
Hogan et al. (1988) studied this question.
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