Population
23 anesthetized dogs
Comparison
Coronary artery ligation combined with either… vs Sham ligation (sham-MI)
Design
Preclinical
Follow-up
Acute
Authors
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Increased lung vascular permeability follows acute MI in canines; leaves open translation to human pulmonary edema mechanisms.
Acute myocardial ischemia in a canine model increases lung vascular permeability, which may be mediated by the activation of formed blood elements.
Gee et al. (1982) studied this question.
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