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June 29, 2020Scandinavian Cardiovascular Journal

NLR (OR 1.107, 95% CI 1.044-1.172, p=0.001), MPV (OR 1.398, 95% CI 1.010-1.937, p=0.044), and PDW (OR 1.392, 95% CI 1.012-1.914, p=0.042) were independent predictors of no-reflow.

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Why the study?

The study was conducted to evaluate the predictive value of NLR, MPV, and PDW for the no-reflow phenomenon in patients with ST-segment elevation myocardial infarction.

Do neutrophil-to-lymphocyte ratio and platelet correlation parameters predict the no-reflow phenomenon after primary percutaneous coronary intervention in patients with ST-segment elevation myocardial infarction?

Population

455 STEMI patients undergoing primary PCI

Comparison

No-reflow group vs control group

Design

Consecutive observational cohort study

Authors

QZQin-Yao ZhangMHMeirong HuJSJiaying Sun

Discussion

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Member takes

Overview

May support NLR, MPV, and PDW for no-reflow risk stratification in STEMI; hypothesis-generating and should not yet change practice.

Structured PICO

Do neutrophil-to-lymphocyte ratio and platelet correlation parameters predict the no-reflow phenomenon after primary percutaneous coronary intervention in patients with ST-segment elevation myocardial infarction?

P
Population
455 patients with ST-segment elevation myocardial infarction who underwent primary percutaneous coronary intervention
I
Intervention
Neutrophil-to-lymphocyte ratio (NLR), mean platelet volume (MPV), and platelet distribution width (PDW) assessment
O
Outcome
No-reflow phenomenonsurrogate

NLR, MPV, and PDW independently predict no-reflow after primary PCI in STEMI patients, though combining them does not improve predictive accuracy over NLR alone.

Cite This Study

Zhang et al. (2020) studied this question.

synapsesocial.com/papers/6a7e4cdb1fdb7ee677c76b26https://doi.org/10.1080/14017431.2020.1783457
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Platelet/ lymphocyte ratio for prediction of no reflow phenomenon in ST elevation myocardial infarction managed with primary percutanous coronary intervention2020 · 7 citations
  2. 2Association between neutrophil to high-density lipoprotein ratio and no-reflow after coronary intervention: A cross-sectional study2025 · 1 citations
  3. 3The Utility of the Platelet–Lymphocyte Ratio for Predicting No Reflow in Patients With ST-Segment Elevation Myocardial Infarction2014 · 101 citations
  4. 4Prognostic Value of Pre-Infarction Angina Combined with Mean Platelet Volume to Lymphocyte Count Ratio for No-Reflow and Short-Term Mortality in Patients with ST-Segment Elevation Myocardial Infarction Undergoing Percutaneous Coronary Intervention2020 · 16 citations
  5. 5Correlation of platelet‐to‐lymphocyte ratio and neutrophil‐to‐lymphocyte ratio with thrombolysis in myocardial infarction frame count in ST‐segment elevation myocardial infarction2017 · 49 citations