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January 7, 2020Medical Science MonitorOpen Access

The combination of MPVLR and PIA effectively predicted no-reflow phenomenon (AUC=0.847, 95% CI: 0.821-0.874) and 90-day mortality (AUC=0.790, 95% CI: 0.725-0.855).

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Why the study?

The clinical predictive value of pre-infarction angina combined with mean platelet volume to lymphocyte count ratio for no-reflow and short-term mortality in STEMI patients undergoing PCI required investigation.

Does the combination of pre-infarction angina and mean platelet volume to lymphocyte count ratio predict no-reflow and 90-day mortality in STEMI patients undergoing PCI?

Population

1009 STEMI patients who had undergone PCI

Comparison

4 groups based on occurrence of PIA and MPVLR above or below cutoff

Design

Cohort study

Follow-up

90 days

Authors

XCXinsen ChenYMYoubao MengMSMeng Shao

Discussion

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Member takes

Overview

May support risk stratification in STEMI PCI; hypothesis-generating and requires prospective validation before practice change.

Structured PICO

Does the combination of pre-infarction angina and mean platelet volume to lymphocyte count ratio predict no-reflow and 90-day mortality in STEMI patients undergoing PCI?

P
Population
1009 patients with ST-segment elevation myocardial infarction (STEMI) undergoing percutaneous coronary intervention (PCI)
I
Intervention
Pre-infarction angina (PIA) combined with mean platelet volume to lymphocyte count ratio (MPVLR)
C
Comparator
Patients grouped by presence/absence of PIA and MPVLR above/below cutoff
O
Outcome
No-reflow phenomenon and 90-day mortalityhard clinical

The combination of pre-infarction angina and MPVLR provides a strong predictive value for no-reflow and short-term mortality in STEMI patients undergoing PCI.

Cite This Study

Chen et al. (2020) studied this question.

synapsesocial.com/papers/6a8a3ad441f4089922bd87afhttps://doi.org/10.12659/msm.919300
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Prognostic value of the combination of GRACE risk score and mean platelet volume to lymphocyte count ratio in patients with ST‑segment elevation myocardial infarction after percutaneous coronary intervention2020 · 19 citations
  2. 2The prognostic value of admission mean platelet volume to platelet count ratio in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention2015 · 26 citations
  3. 3Predictive Value of Mean Platelet Volume/Platelet Count for Prognosis in Acute Myocardial Infarction2018 · 36 citations
  4. 4The prognostic value of mean platelet volume to platelet count ratio in older patients with non-ST elevation acute coronary syndrome receiving primary percutaneous coronary intervention: a retrospective study2019 · 3 citations
  5. 5Prognostic value of platelet indices after acute myocardial infarction treated with primary percutaneous coronary intervention2013 · 99 citations