Why the study?
Does the one-kidney, one clip hypertension model alter plasma and atrial ANF levels in rats?
Does the one-kidney, one clip hypertension model alter plasma and atrial ANF levels in rats?
High levels of plasma ANF in 1K1C hypertensive rats are likely secondary to increased intra-atrial pressure and normalize after unclipping.
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ANF elevation may mark atrial pressure in experimental renovascular hypertension; leaves open human relevance and therapeutic implications.
García et al. (1987) studied this question.
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