Why the study?
Does benazepril improve functional class compared to hydrochlorothiazide in post-infarction patients with mild symptomatic heart failure?
Population
29 post-infarction patients with symptomatic mild heart failure. No concomitant drug therapy was given.
Comparison
Benazepril 20 mg daily for a 3-month treatment… vs Hydrochlorothiazide 50 mg daily for a 3-month…
Design
RCT, double-blind
Follow-up
3-month treatment periods
Authors
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Benazepril improves NYHA class over hydrochlorothiazide in post-MI mild HF; supports ACE inhibitor preference in this population.
Does benazepril improve functional class compared to hydrochlorothiazide in post-infarction patients with mild symptomatic heart failure?
Benazepril is superior to hydrochlorothiazide in improving functional class and global efficacy in patients with mild symptomatic heart failure post-myocardial infarction.
Nordrehaug et al. (1992) studied this question.
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