Population
Normotensive offspring of hypertensive parents (OHyp) and patients with essential hypertension
Design
Review
Authors
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May support ANF-activating therapies in essential hypertension; leaves open prospective validation of this postulated deficiency syndrome.
A relative deficiency in atrial natriuretic factor (ANF) may predispose individuals to essential hypertension, providing a rationale for treatments that activate the ANF system.
Weidmann et al. (1991) studied this question.
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