Why the study?
Does nifedipine retard improve cardiac remodeling and function compared to ACE inhibitors in hypertensive patients with coronary artery disease?
Population
210 hypertensive patients with coronary artery disease
Comparison
Nifedipine retard for 3 years vs Angiotensin-converting enzyme inhibitors for 3…
Design
RCT, randomly assigned
Follow-up
3 years
Authors
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Either agent supports reverse remodeling in hypertensive CAD; confirms BP lowering drives functional gains regardless of class.
Does nifedipine retard improve cardiac remodeling and function compared to ACE inhibitors in hypertensive patients with coronary artery disease?
Blood pressure lowering with either nifedipine retard or ACE inhibitors leads to comparable reverse remodeling and improved cardiac function in hypertensive patients with coronary artery disease.
Yui et al. (2009) studied this question.
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