Why the study?
Does intravenous endothelin-1 reduce coronary blood flow in healthy volunteers?
Population
6 healthy volunteers
Design
Other
Follow-up
60 minutes after infusion
Authors
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Suggests ET-1 coronary vasoconstriction in humans; hypothesis-generating for its role in ischemia.
Does intravenous endothelin-1 reduce coronary blood flow in healthy volunteers?
Intravenous endothelin-1 induces a long-lasting reduction in coronary blood flow and increases coronary vascular resistance in healthy humans.
Pernow et al. (1997) studied this question.
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