Why the study?
Does withdrawal of amantadine precipitate neuroleptic malignant syndrome in hyperpyrexic patients?
Population
A patient with neuroleptic malignant syndrome following withdrawal of neuroleptics and amantadine
Design
Case_report
Authors
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Supports avoiding abrupt amantadine withdrawal in neuroleptic-treated patients; hypothesis-generating case report requiring confirmation.
Does withdrawal of amantadine precipitate neuroleptic malignant syndrome in hyperpyrexic patients?
Dopamine agonists should not be discontinued in hyperpyrexic patients at risk for neuroleptic malignant syndrome.
Simpson et al. (1984) studied this question.
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