Population
Isolated mouse renal juxtaglomerular (JG) cells in short-term cultures
Comparison
Second-messenger molecules including… vs Basal conditions (untreated cells)
Design
Preclinical
Follow-up
20-hour incubation period
Authors
Loading...
Should not yet change clinical renin management; leaves open cAMP pathway targeting pending in vivo confirmation.
In isolated mouse juxtaglomerular cells, cAMP acts as a positive signal for both renin secretion and synthesis, while second-messenger control of these two processes is not tightly linked.
Bruna et al. (1991) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: