Why the study?
Do exercise-related factors such as chronotropic incompetence and heart rates exceeding the device upper limit predict response to cardiac resynchronization therapy in patients with severe heart failure?
Population
144 consecutive patients with severe heart failure and mechanical dyssynchrony undergoing cardiac…
Design
Cohort
Follow-up
6 months
Authors
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Exceeding device upper rate limit during moderate exercise may predict CRT nonresponse; hypothesis-generating for rate optimization trials.
Do exercise-related factors such as chronotropic incompetence and heart rates exceeding the device upper limit predict response to cardiac resynchronization therapy in patients with severe heart failure?
Heart rates exceeding the device's upper tracking limit during moderate exercise predict CRT nonresponse in patients with atrial fibrillation, whereas chronotropic incompetence predicts nonresponse in those with sinus rhythm.
MAASS et al. (2009) studied this question.
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